Today's Articles


Question:

>Any kind of extra bacterial load may aggravate psoriasis.

True.  When I had my cellulitis infection in the rash from my Enbrel allergic reaction (long story), I flared up in skin psoriasis all over, maybe 90% coverage in one DAY.  Pretty scary I tell you… When I discussed it with the dermatologist, he said it is not uncommon; any kind of bacterial infection can cause a flare in psoriasis. Happily mine was very temporary; once I was put on heavy-duty antibiotics for the infection, my skin calmed down and with the help of some Dovonex ointment, went back to its previous very low coverage of maybe 5 percent or less. LadyAndy Chat live with us at >http://tinyurl.com/4ust < (this is at iVillageHealth – my chats are on Sun evenings at 10 ET) Joint Replacement Board at http://boards.ivillagehealth.com/cgi-bin/boards/bhivhjointreplace

Response:

Now that you mentioned it.  I am also living in pain due to bad teeth.  Now I think maybe there is a connection with p. David

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>Now that you mentioned it.  I am also living in pain due to bad teeth.  Now >I think maybe there is a connection with p. >David

Hey David, whether it is related to the Ps or not, you need to get that taken care of.  If money is the problem, try asking around with some dentists asking if they can help you and offer you payment terms.  You’d be surprised how much some of them will bend over backwards to help out somebody who needs it. You can also post to sci.med.dentistry for some frank replies from several dentists and other dental specialists.  Yeah, there’s some weird stuff there too, but hey, this is Usenet.  :) LadyAndy Chat live with us at >http://tinyurl.com/4ust < (this is at iVillageHealth – my chats are on Sun evenings at 10 ET) Joint Replacement Board at http://boards.ivillagehealth.com/cgi-bin/boards/bhivhjointreplace

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>> Don’t know if the dental problems are a definite link for sure. And if it was, > it could have been the stress from the whole situation, or the infection, or > both. >According to my dermatologist and most things I have read, quite often the first >onset of psoriasis comes about during a time of stress. I would say that two >abscessed teeth would qualify very well.

Any kind of extra bacterial load may aggravate psoriasis. Haven’t they reported a couple of times in recent years that heart disease correlates to arterial inflammation correlates to dental hygiene?  Brush your teeth, protect your heart, and maybe reduce your psoriasis, at least a tad. J.

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- Hide quoted text — Show quoted text – > Yo I can relate to this. > I had 2 abcessing teeth and a couple of cavites for about 18months because I > didn’t have the money to get them fixed with a dentist. about 6 months into the > painful ordeal I got P for the the first time and had it ever since. > Now I just got my teeth fixed (2 root canals, 5 fillings and a deep cleaning > Its been about a week since my last dentist appointment and my P is  a little > better. Which suprised me becasue it should be worse seeing as I havent gone to > the tanning bed in awhile. > Don’t know if the dental problems are a definite link for sure. And if it was, > it could have been the stress from the whole situation, or the infection, or > both.

According to my dermatologist and most things I have read, quite often the first onset of psoriasis comes about during a time of stress. I would say that two abscessed teeth would qualify very well. — Chuck "If you once forfeit the confidence of your fellow citizens, you can never regain it. It is true that you may fool all of the people some of the time; you can even fool some of the people all of the time; but you can’t fool all of the people all of the time." Abraham Lincoln

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I am curious if anyone has had any experience with decaying/impacted/infected wisdom teeth triggering psoriasis.  I had no signs of psoriasis until about two years ago.  My wisdom teeth first popped up four or five years ago.  Now one tooth bothers me on, and off, and I have little doubt that it is infected.  I plan on having all four removed soon.  Any experiences, or guesses would be appreciated. Jeffrey Wilk

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Yo I can relate to this. I had 2 abcessing teeth and a couple of cavites for about 18months because I didn’t have the money to get them fixed with a dentist. about 6 months into the painful ordeal I got P for the the first time and had it ever since. Now I just got my teeth fixed (2 root canals, 5 fillings and a deep cleaning Its been about a week since my last dentist appointment and my P is  a little better. Which suprised me becasue it should be worse seeing as I havent gone to the tanning bed in awhile. Don’t know if the dental problems are a definite link for sure. And if it was, it could have been the stress from the whole situation, or the infection, or both.

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Question:

>Well, the psoriasis never really vanishes, but at least there was no flaking, >itchin or bleeding.  Skin was as slick as a baby’s.

Ohhhhhh … Derm said (a) neoral clears some large percent, (b) p comes back, but weeks or months (or more) later. So, yes, you’d still want to take care, but I guess he had in mind an on-and-off utilization. Now, if you’re saying that even the "clear" areas do not really, really clear, well, I see why one would stay on it continuously, as long as possible. Thanks for the info. J.

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>Derm said (a) neoral clears some large percent, (b) p comes back, but >weeks or months (or more) later. >So, yes, you’d still want to take care, but I guess he had in mind an >on-and-off utilization. >Now, if you’re saying that even the "clear" areas do not really, >really clear, well, I see why one would stay on it continuously, as >long as possible.

One of the strategies I’ve heard for when using methotrexate to treat skin psoriasis only is to use the MTX only as long as it takes to get the skin clear enough that topical, less-powerful drugs could "take over" and have a chance of working (in other words, clear enough that it doesn’t take 10 hours to apply, say, coal tar).   Of course, this requires at least *some* of the patches to actually go away completely. And, if after stopping the MTX, patches start coming back, they get treated "agressively" with topicals while they’re still small. Depending on the individual case of psoriasis, it might be possible to use Neoral in this way, also. – Dave W. http://members.aol.com/psorsite/

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>I have just found this newsgroup and feel that i should contribute by telling >you all that i have been prescribed Neoral tablets for my skin it really does >get ridl

Neoral : Isn’t that Cyclosporen? Tell us about side effects and your dosage if you could . Thanks alot.

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Yes, Neoral does work on some people.  It is not for the chronically ill and you really have to have a severe case of psoriasis to justify it’s use.  There are side effects and this powerfull "anti-rejection" drug requires very close monitoring for kidney damage. I was on the drug for 10 months and it was glorious.  Almost total clearing in 10 days or so.  Side effects were minimal insofar as digestive and stomach problems.  I did have headaches and fatigue sometimes.  I developed a high pulse rate and high blood pressure from it.  When the Labs started to show too much "out of limit" readings, I stopped and had a consult with a nephrologist. There was some kidney reduction in activity and it was suggested that I stop the Neoral for a few weeks.  Two weeks after stopping, blood pressure and pulse rate returned to normal.  Also, lipids and gllucose values were back to almost "normal." Now that I am using no Meds, skin has deteriorated a bit, but the last 10 months were the greatest in 20 years.  One needs to do a lot of reading on Neoral and a lot of risk analysis; it is serious business with the potential for great harm. "With psoriasis, one never really knows." Irv—>Alabama "and don’t give up – ever"

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>I was on the drug for 10 months and it was glorious.  Almost total clearing in >10 days or so.  

Irv, If you cleared in ten days,  why were you on the drug for ten months? One derm I’ve seen suggested going on neoral for thirty days. I’m just trying to understand the logic behind the usage. Thanks. J.

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I think the reason for staying on it is because once you stop the psoriasis comes back. Is this correct Irv?

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Well, the psoriasis never really vanishes, but at least there was no flaking, itchin or bleeding.  Skin was as slick as a baby’s.  For some, after suspension of Neoral, activity can start at any time, but for others several months go by and it provides a false sense of security…  One still has to take care of the skin, maintain a good "mental" outlook and eat properly. IMO, it’s what is "inside" that counts.  I do recognize that many who are aflicted do have very painful and disabling aspects of other collateral problems…   But as I have often said, "don’t give up – ever." If illness and disease were fun, everybody would be doing it.  People here are brave and loyal.  I could not have come this far without them, and "we are not alone here." Irv—>in Alabama

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I have just found this newsgroup and feel that i should contribute by telling you all that i have been prescribed Neoral tablets for my skin it really does get ridl

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Had it too last year, worked wonders for me aswell. Misty. – Hide quoted text — Show quoted text -> I have just found this newsgroup and feel that i should contribute by telling > you all that i have been prescribed Neoral tablets for my skin it really does > get ridl

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Question:

Irv, Great to hear that you are already doing so much better!!!! I know several who have been on Neoral (Sandimmun Neoral here in Norway), and they have so much positive to say about this drug even if it is a "tough drug". Neoral has the power to change people’s lives, that is for sure! We (my derm and I) discussed a possible change to Neoral recently, but have (for now) decided to stick with Methotrexate. I have an appointment soon to get an ultrasound of my liver, as I am not willing to have a liver biopsy because of the dangers with such an invasive procedure since I have Ehlers-Danlos Syndrome too. If the ultrasound shows anything, we will also order a scintigraphy (like a bone scan) of the liver too. These two tests should be quite good at showing the state my liver is in. I have now passed the 2 gram limit of MTX after being on it first about two years and this time three years in April. Dave, I am not all that surprised that you don’t have any effect of the MTX yet. First of all you are on a very low dose for skin psoriasis, second it often takes longer to kick in. My experience is about 12-14 weeks. Maybe it would be a good idea to up the dose quite a lot until it kicks in and gets your P.  down to a reasonable level before you start tapering it down to a lower maintenance dose. My experience has also been that (at least for me) it is much more effective if it is injected. Maybe you could ask your doc about a change to injecting it subcutaneously? I am injecting 10 mg weekly. It does not keep me P. free, but it is much more manageable – I have less and it is not so aggressive. Right now I have forgot a dose, and I’m flaring. Last night I had to take one of my "itching pills", because I itched so terribly, no chance of getting any sleep with that itching.  Right now I have just taken two allergy pills in hopes that it will alleviate the itching without the drowsiness the other "itching pills" causes. I slept until noon today because of that one pill I took last night, that and the new pain medication I’m on, I guess. Wonderful to wake up without the normal joint and muscle pain!!!! — Best regards / Med vennlig hilsen, Aase Marit :) ("Aw-Se-Mareet" from Norway)

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>It occurs to me that if you have been using potent >steroids on an on-going basis then the the MTX is >having to counteract the rebound from these. This could >certainly be the reason for the worsening you have >mentioned over the last two years – if you stop using >skincap it ALWAYS gets worse. >So try, hope, pray but DONT give up.

The steroids I’ve used in the past, with the consent of my derm, on mu "privates" and groin areas were mildly potent (clobetasone, not the ultra potent clobetasol) and then usually 3 or 4 applications and is was cleared for weeks, so I’m not sure about rebound effect here.  I concede that I may have rebound from skincap but evern then I was using it judiciously, suspecting all along that steroids were in it (I got my derm to get it analysed roughly the same FDA found out about the clobetasol). I would only use it sparingly. No, I believe that the reason for my P worsening in the last two years is that before then I would go on 2 long holidays a year to the far east and soak up the sun..(this would completely clear the P for about 3 months each time).  Two years ago I had the stress of becoming a father for the first time, no more long haul holidays to Bali (no more hot holidays full stop!) and I gave up (successfully) smoking which was a shock to my system after 20 years of smoking 20 a day. It just came on like a steam train all over my hands and palms and feet/soles where it had never appeared before.  If it was a rebound from skin cap, then 4 courses of UVB (never as good as the real thing in my experience) and 5 months on cyclosporin and now 8 weeks on MTX have failed to knock it back. I’m hoping that a higher dose will sort things out or may be combined UVB/MTX. Thanks for your response anyway — Dave Bentley

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Paul Hi and thanks for your comments. I’m going to ask to go on a higher dose and if that fails after a few weeks I may consider another course of UVB as I have the same model UVB lamp at home that the BUPA hospital in Leicester has (bought it second- hand with new bulbs from Dr Honle UV Technologie in Birmingham who supply hospitals etc (2000 ukp thogh…ouch!) and Its been 4 months now since I last had a dose. For people with busy lives who can’t get down to the hospital 3 times a week for UVB treatment, I would suggest you ask your derm if he would agree to you buying a unit for home use. — Dave Bentley

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– Hide quoted text — Show quoted text -> Hi All > I’ve now been on methotrexate at a dose of 10mg weekly for 7.5 weeks > with little of no improvement (my hands may look less angry, but the > number of lesions is the same and my legs, and all over my feet and in > my armpits/groin/penis are, if anything, worse).  After 15 years my P is > now the worst it has ever been and I’m not sure why. > Was it because I gave up smoking, quit skin cap, became a father all at > the same time 2 years ago?  I don’t know, but as well as being > unsightly, this P in my groin and armpits is actually getting very > uncomfortable, never mind the negative affect it is having on my sex > life and the fact that cycling which I like to do to keep fit actually > makes it worse around the groin.  Treatment with a mild steroid/nystatin > cream which once would put it into remission in that area for weeks, now > just puts it into remission for only  a few days > I’ll be seeing my derm in 10 days time and will probably be told that > the dose needs to go up.  Even if it does eventually clear up I’ve read > that a lifetime dose of 4.5g gives a 25% risk of Liver > cirrhosis…great!   I guess this means that MTX will be a temporary > treatment  rather than a lifetime treatment. > This disease is a real bummer.   > What experiences have other people had with MTX.  If they didn’t clear > at 10mg what dose did they need and how quickly did it start to work.

My 13 year old son has had P and PA for 4 years now and been on Dovonex and most other topical treatments until the Derm gave up and suggested MTX some 3 months ago. After 2 weeks agonising (I have followed this NG for years now) over the side effects and risks we agreed. He is on 10mg a week in a single dose and improvement started after 2 weeks. I think hes been on it for about 10 to 13 weeks and although not completely clear (we cant ask for miracles can we!) the worst areas (the arms, legs and groin) are almost clear. The chest and back have small spots (looks like guttate which is how he started) but the large plaques have gone. He does suffer from side effects – mainly loss of appetite and tiredness especially on the day of taking it and the day after but for the moment he is prepared to put up with this. The problem with MTX is that it works slowly. An increase in dosage would also help but not instantly. Strangely the MTX has not helped the PA. His toe nails, which were really bad, are now back to normally. The lifetime dose is a bummer isn’t it. The derm says that if we reach complete clearance we stop the MTX – and wait to see what happens. All in all though it has definitely been worthwhile even if we have to stop tomorrow – we are currently back where things were 3 years ago and those 3 years have been a steady slide down the slope. It occurs to me that if you have been using potent steroids on an on-going basis then the the MTX is having to counteract the rebound from these. This could certainly be the reason for the worsening you have mentioned over the last two years – if you stop using skincap it ALWAYS gets worse. So try, hope, pray but DONT give up. — Kevin Campbell Northumberland England The home of Hadrian’s Wall

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Dave, Hello. I

Question:

Derek and Gayle – There is a better way.  You can get rid of both your psoriasis and your psoriatic arthritis by healing your body, not by taking dangerous expensive drugs.  Scientific and medical research has shown your body is deficient in certain things.  When you take those things your body needs, avoid the things you are allergic to, make a few lifestyle changes [no alcohol, no smoking, etc.], and reduce your stress level, you can get rid of your psoriasis.  If you want to know more, check out www.psoriasiscure.net. LD – Hide quoted text — Show quoted text -> Derek – I developed psoriasis, psoriatic arthritis and Multiple Sclerosis > all within a month of each other 13 years ago.  Yes, for me, the arthritis > has stayed in my hands and feet, with the exception of one elbow of late. > I have begun taking methotrexate for the psoriasis – so far it has cleared > up my fingernails, but skin is the same.  Hope more time will make more of a > difference. > Voltarin is an excellent medication (anti-inflamatory) for it, but it’s > excpensive.  Hope you have prescription coverage – i don’t and had to quit > taking it. > Good luck!! > Gayle >Can anyone shed some light my way?  I’m 22, and I could probably give my >grandmother’s complaints a run for their money.  My knees ache all the >time, although my psoriasis is limited to my hands, face, and scalp. >Does psoriatic arthritis tend to stay in affected areas (hands, in my >case) or does it have a mind of its own?

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by healing your body, not by taking dangerous expensive drugs.  Scientific and medical research has shown your body is deficient in certain things. When you take those things your body needs, avoid the things you are allergic to, make a few lifestyle changes [no alcohol, no smoking, etc.], and reduce your stress level, you can get rid of your psoriasis.  If you want to know more, check out www.psoriasiscure.net. >>
sheesh, that makes it sound soooooo easy! "reduce your stress level" ?! as if it was as simple as cutting down on the amount of sugar you have in your coffee! how about some suggestions? "make a few lifestyle changes". ok, i =know= that it makes my skin worse, but it’s not easy when all your friends drink, and when much of your socialising is done in the pub. there’s nothing more boring than watching other people get drunk, is there? :) and, yeah, i have tried a no-sugar/no-salt/no-meat/-no-wheat/no-dairy diet (as reccomended by a naturopath), but it’s a =lot= easier to do that when you have someone else to do it with, or when someone is preparing your food, as in my case (i was 9 at the time) i don’t know anyone who’s prepared to make such sacrfices now, not to mention the fact that the food i had to live on then makes me feel sick now! so, any suggestions? yeah, and i’ve tried dovonex, betnovate, betcap, polytar, alphosyl and homeopathy but the steroid ointments only make it come back twice as worse, =and= mess up my hormones to boot (spots, painful periods etc) the only thing to shift it and keep it shifted is sunshine. does anybody take vitamin e suppplements and do they help? did you have to get them prescribed or can you get them over the counter (i live in the uk). and, finally getting back on-topic, i get arthritic pains in my two big toes which sometimes makes it hurt when i walk, but other than that, i’ve been lucky.
sorry this is long, thought it might help to know where i’,m coming from :)

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As others have said, you need a rheumatologist.  Other specialists will often either never have seen or never have diagnosed correctly PA in their practices.  Yes, a dermatologist may well be informed about PA (unlike other kinds of physicians), but the rheumatologist is the one with experience with PA and the treatments used for it. I found my PA to start out sort of like "jumping" from joint to joint.  I might be limping around with an unhappy hip for a month or two, and then it would go away.  Then maybe an ankle would swell up and hurt for a while… then that would go away. However, I did reach a point where it really flared bigtime.  My knees swelled up like honeydew melons and I suddenly couldn’t straighten them out (contractures).  In time, I developed PA in all my joints and now have it everywhere. PA can be aggressive if left untreated.  NSAID’s and over-the-counter med’s can only do so much.  If you are having progression of the symptoms, flaring of the joints, heat from the joint, redness, pain, inflammation, and general increase in symptoms, DO NOT DELAY getting to a rheumatologist.  NSAID’s can help with symptoms, but they do NOT treat the underlying disease progression.  That requires more aggressive treatments, like the DMARD’s (disease modifying anti rheumatic drugs), such as MTX (methotrexate).   You can read more about all this at the following noncommercial website: http://www.aztec.co.za/users/drdoc/ This is the site of a practicing rheumatologist in South Africa… the home page takes a minute or so to download.  Then start with "Index Pages"… then click "Diseases"… then click "Psoriatic Arthritis".  You will find that there are different types (5) that affect different patterns of joints typically, although there can be variation. By the way, I have had 2 total knee replacements and one total hip replacement because of my PA.  If I can answer any other questions, I’ll be happy to… although I’ll be out of town for 4 days.  :) Best regards,

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so, can my dermatologist tell me if it’s PA or do I get to find yet another doctor?

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My PA is also quite independent. I have it in the tendons that move the fingers, but have no P on the hands (not under the nails, either). I have P on the left knee, with no PA; but no P on the right knee, which has had PA. I have an excellent dermatologist, but I don’t think he knows much about PA at all – I’d suggest seeing a rheumatologist.

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> so, can my dermatologist tell me if it’s PA or do I get to find yet > another doctor?

    I suspect that PA isn’t necessarily the strongest area of your dermy’s expertise, so chances are good that you’ll need a referal to see a rheumatologist (arthritis specialist).   Your dermy might generally agree with a tentative PA diagnosis, but even if that happened you’d need to find an RD to get   specific advice to move forward with treatment options.     The main thing my dermy did for me was confirm the presense of psoriasis thereby opening the door for consideration of PA. Without the skin psoriasis my condition would have been very difficult to place – I got the impression that up till that point the RD was leaning more in the direction of "Reuter’s Syndrome" (a bacterial infection that typically goes after the hips and lower back). — Nathan Engle               Electron Juggler Indiana University         Dept of Psychology "Some Assembly Required"

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>Does psoriatic arthritis tend to stay in affected areas (hands, in my case) or

does it have a mind of its own?>> My experience is that it is unpredictable.  I’ve had it in some joints chronically, then everywhere, and then it cleared up completely (with no prescription drugs) after a few years of total misery.  After several years of remission, I had a relapse lasting about a few months that was severe, and now it’s gone again.  It is not always the same joints that are affected, although I do notice a tendency for my left wrist to signal trouble is starting for my body.  I’m still trying to figure out what triggers or aggravates it (although I have some theories, they don’t always work in practice).

Response:

Derek – I developed psoriasis, psoriatic arthritis and Multiple Sclerosis all within a month of each other 13 years ago.  Yes, for me, the arthritis has stayed in my hands and feet, with the exception of one elbow of late. I have begun taking methotrexate for the psoriasis – so far it has cleared up my fingernails, but skin is the same.  Hope more time will make more of a difference. Voltarin is an excellent medication (anti-inflamatory) for it, but it’s excpensive.  Hope you have prescription coverage – i don’t and had to quit taking it. Good luck!! Gayle – Hide quoted text — Show quoted text – >Can anyone shed some light my way?  I’m 22, and I could probably give my >grandmother’s complaints a run for their money.  My knees ache all the >time, although my psoriasis is limited to my hands, face, and scalp. >Does psoriatic arthritis tend to stay in affected areas (hands, in my >case) or does it have a mind of its own?

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I have PA affecting mainly my knucle joints, feet, and to a certain extent my elbows. I also have bad nails, but no other skin related problems. I take anti-inflammatory  drugs, and have just been prescribed Meloxicam, which I belive is fairly new. I have been referred, but waiting for an appointment. I am 43. Paul – Hide quoted text — Show quoted text – >Can anyone shed some light my way?  I’m 22, and I could probably give my >grandmother’s complaints a run for their money.  My knees ache all the >time, although my psoriasis is limited to my hands, face, and scalp. >Does psoriatic arthritis tend to stay in affected areas (hands, in my >case) or does it have a mind of its own?

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Can anyone shed some light my way?  I’m 22, and I could probably give my grandmother’s complaints a run for their money.  My knees ache all the time, although my psoriasis is limited to my hands, face, and scalp. Does psoriatic arthritis tend to stay in affected areas (hands, in my case) or does it have a mind of its own?

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> Can anyone shed some light my way?  I’m 22, and I could probably give my > grandmother’s complaints a run for their money.  My knees ache all the > time, although my psoriasis is limited to my hands, face, and scalp. > Does psoriatic arthritis tend to stay in affected areas (hands, in my > case) or does it have a mind of its own?

    My PA affects my knees, hips, and hands.  My scaling is pretty much limited to my scalp and face, although I’ve also got disintegrating nails on both fingers and toes.     So I guess the short answer is "mind of its own". — Nathan Engle               Electron Juggler Indiana University         Dept of Psychology "Some Assembly Required"

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Question:

Michelle, Welcome. >The most pain is >in my "ring toe" which looks so deformed it’s embarrassing!!  Does anyone >have any advice about learning to deal with the deformity part.

I’ve got PA and have had problems with my toes, also.  Unfortunately, I don’t have any answers on the existing deformity.  One of my toes in now a ‘hammer toe’ and another looks like it has become partly fused.  I asked my doctor about the possibility of getting one amputated and he just laughhed.  I don’t think he took me seriously.  I had more important things to discuss so I didn’t follow it up. One thing that I’ve figured out is that when my toes are inflamed I need larger shoes.  It seems obvious to me now, but it took me a long time to figure it out.  And unfortunately, it’s probably too late for some of my toes…  I think a lot of the problem was caused by the fact that my toes were jammed into a shoe that was no longer large enough for them.  This probably won’t help reverse any existing damage that has already been done, but hopefully will limit any future damage and pain.  Since my inflamation is very seasonal, I now have summer shoes (size 12) and winter shoes (size 13).  Could this you help you any? >Or just to hear someone elses complaints.

We’ll see what we can do about coming up with some complaints.  :-) >Also, I’ve only seen a doctor once for it. >I could also use some advice on the availability of medications, etc.

I hope you’re seeing a rheumatologist!  If you’ve gotten to the point that you have deformity, then you really should be seeing one. Good luck, Rick G(in CA)

Response:

Welcome Michelle! You’ve already gotten some great advice so I just thought I’d chime in about the having kids part.  If your doctor is referring to Prednisone, it is in fact safe to take during pregnancy. I’m pregnant right now and did lots of research and found it does not cross the placenta. I took it during the first few weeks of pregnancy but haven’t needed it since. I’m not sure if women with PA go into remission during pregnancy but you might want to check with a rheumatologist.  I wouldn’t have attempted pregnancy without talking a lot with mine. Good luck!! Carina – Hide quoted text — Show quoted text ->Hi, I’am a 32 year old female and have been suffering with PA for a few years >now. I have been affected by it in my fingers and in my toes.  The most pain >is >in my "ring toe" which looks so deformed it’s embarrassing!!  Does anyone >have >any advice about learning to deal with the deformity part.  Also, I’ve only >seen a doctor once for it.  He wanted me to start taking some kind of Steroid >however I hadn’t had any children yet, so he advised me not to take it.  I >have >never met anyone else with the illness so I’d love to hear from anyone who >can >help me in any way. Or just to hear someone elses complaints.  I could also >use >some advice on the availability of medications, etc. Thank you so much!! >Michelle.

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Hi Michelle I have PA and I hate the deformties of my ring toes,they are so swollen and my pointy fingers on my hands and the knuckles are all swollen and deformed. I take MTX it but it gets me down sometimes and I snap at my hubby sometimes. I dont like to be depending on other people all the time,I like to be independant. Hope one day it will get better. Cheryl                              Cheryl & Kevin Page us: http://wwp.mirabilis.com/270914 Kevin’s Page: http://www.freeyellow.com/members2/ddkr/kev0.html Cheryl’s Page: http://www.freeyellow.com/members2/ddcr/cue_t.html <<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<< begin 666 cheryl.vcf M0D5′24XZ5D-!4D0-"E9%4E-)3TXZ,BXQ#0I..CMC:&5R>6P-"D9..F-H97)Y M; T*14U!24P[24Y415).150Z9&1K<D!A;&IA;BYC;VTN874-"D5-04E,.U!2 55# Y,38P-%H-"D5.1#I60T%21 T* ` end

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Hi, Michelle! Steroids aren’t contraindicated in child bearing years in general. But, systemic steroids are contraindicated for people with psoriatic arthritis. The reason is that they can cause a bad flare-up of psoriasis and even change ordinary psoriasis to the generalized form of pustular psoriasis. That can be serious. Intraarticular steroid shots are OK though (shots into the joint). Another medication commonly used in RA is Plaquenil (anti-malarial). That may also worsen skin psoriasis. In some cases they now chose to use it anyway and to handle a flare-up of P. if it happens. Commonly used long acting medications (DMARDS) are: Salazopyrine/sulphasalazine Methotrexate Cyclosporine I am not sure for sulphasalazine or cyclosporine, but methotrexate you can use until 6 months before you try to conceive. While you are on it and 6 months after you have to be on safe birthcontrol. Other commonly used medications are the non steroidal anti-inflammatory drugs – NSAIDS. In light cases that is often the only medication used. I agree with the others, you should see a rheumatologist! Goto drdoc’s page for more information. Also make sure to read the page about preparing for a doc’s visit. Take care!!! > As for steroids, Prednisone is often a first line of defense in the > treatment of inflammatory arthritis, but as far as I know it is not > contraindicated in child bearing years.

– Best regards / Med vennlig hilsen,       Aase Marit :) ))))))            ("Aw-Se-Mareet" from Norway) http://w1.2380.telia.com/~u238000263/flaker/docs/index.html

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Michelle-The first thing you need to do is get in to see a Rheumatologist.   There are over 100 different kinds of arthritis and the treatment is specific for each type of arthritis. As for steroids, Prednisone is often a first line of defense in the treatment of inflammatory arthritis, but as far as I know it is not contraindicated in child bearing years.  Many of the ladies here are mothers of young children, at least one is pregnant, and several are trying to get pregnant.   Some of the Disease Modifying Drugs (DMARDs) are contraindicated if you are trying to become pregnant. But Prednisone, as far as I know, is safe.  Of ten yourng women will go into remission while pregnant.  But the only way to get really good answers to that are pertinent to you is to see a Rheumatologist..  Please let us know what happens. Char Le Fleur Iowa,   USA – Hide quoted text — Show quoted text – > Hi, I’am a 32 year old female and have been suffering with PA for a few years > now. I have been affected by it in my fingers and in my toes.  The most pain is > in my "ring toe" which looks so deformed it’s embarrassing!!  Does anyone have > any advice about learning to deal with the deformity part.  Also, I’ve only > seen a doctor once for it.  He wanted me to start taking some kind of Steroid > however I hadn’t had any children yet, so he advised me not to take it.  I have > never met anyone else with the illness so I’d love to hear from anyone who can > help me in any way. Or just to hear someone elses complaints.  I could also use > some advice on the availability of medications, etc. Thank you so much!! > Michelle.

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Michelle, What LadyAndy2 said!  She says it so much better than I.  Welcome. Crystal soon to be Ramblin Rose again

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>Hi, I’am a 32 year old female and have been suffering with PA for a few years >now. I have been affected by it in my fingers and in my toes.  The most pain is >in my "ring toe" which looks so deformed it’s embarrassing!!  Does anyone have >any advice about learning to deal with the deformity part.  Also, I’ve only >seen a doctor once for it.  He wanted me to start taking some kind of Steroid >however I hadn’t had any children yet, so he advised me not to take it.  I have >never met anyone else with the illness so I’d love to hear from anyone who can >help me in any way. Or just to hear someone elses complaints.  I could also use >some advice on the availability of medications, etc. Thank you so much!! >Michelle.

Hi Michelle! I have PA also and so do several people here. It’s in my fingers and toes also, seems like those are common targets. The only advice I can give you is to find a good rheumatologist. There is a new PA e-mail list at http://www.onelist.com/subscribe.cgi/ you might check it out! Steve http://www.zoomnet.net/~steve

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You need to be seeing a rheumatologist! If the joints are already deforming, you best be doing something to slow it down!! As for the deformed toes…..I say ewwwwwww!!!!!! Wear shoes and socks at all times! That’s what I do!!! Keep Smilin’ ~krissy Visit my web pages at: http://arthritisnet.com http://members.aol.com/KrissyJo/RA.html "The most thoroughly wasted of all days is that  in which one has not laughed." Nicolas Chamfort

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Hi, Michelle… welcome to the group!  As the others have said, you really need to be in the care of a rheumatologist.  Deformities caused by PA are not to be played around with… I know, I have PA too, and have had 2 tkr’s and 1 thr so far.   A good rheumy will also be able to help you decide what medications you may be able to take and for what period of time to get the PA under control while managing the child bearing question.   You can read more all this at the following non-commercial web site: http://www.aztec.co.za/users/drdoc/ Best regards, LadyAndy2

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Hi, I’am a 32 year old female and have been suffering with PA for a few years now. I have been affected by it in my fingers and in my toes.  The most pain is in my "ring toe" which looks so deformed it’s embarrassing!!  Does anyone have any advice about learning to deal with the deformity part.  Also, I’ve only seen a doctor once for it.  He wanted me to start taking some kind of Steroid however I hadn’t had any children yet, so he advised me not to take it.  I have never met anyone else with the illness so I’d love to hear from anyone who can help me in any way. Or just to hear someone elses complaints.  I could also use some advice on the availability of medications, etc. Thank you so much!! Michelle.

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Hi Michelle, Sorry you have a reason to be here, but welcome!  You said you have only seen a doctor once, was it a rheumatologist?  If not, you should really see a rheumatologist.  There are many forms of treatment available, some more agressive than others.  I can understand your hesitation since you still want to have children, but a rheumy could help you make the right decisions about what treatments would be right for your situation.  Whatever your decision, hang around here.  This is a great place, full of support and friendship.   Take care, Bonnie Never enter into a battle of wits with an unarmed opponent :o )

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Question:

Hi Bruce,   I too was on high doses of nsaids and they did nothing but give me stomach problems.  I’m on HYDROCHLORIQUIN (plaquinil) now.  I haven’t had any side effects form it so far and when I asked my eye doctor about problems he said CHLORIQUIN was the drug that caused problems.  NOT HYDROCHLORIQUIN.  I’m not familiar with  PA I have RA but I hope this helps. Erin

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Hi Bruce, In case no one has beat me to it, welcome to the sandbox!  My arthritis is more RA than PA, but I’ve been on Plaquenil since Dec ‘96.  It worked well for me the first year with no side effects, but seems to be losing its umpf.   Make yourself at home and keep posting! Barbara Joy – Hide quoted text — Show quoted text – > My rheumatologist and I are not impressed with the results of high doses > of nsaids in treating my PA.  As a result she wants to put me on disease > modifying medication.  Because of another disease and the meds i take > for it the only one she is comfortable using at this point is > chloriquin.  Has anyone taken this durg?  Success/side effects? > Thanks    Bruce

Response:

Bruce, You should be aware of the fact that anti-malarials normally are contraindicated in psoriatic arthritis. The reason is that it may cause a big flare-up of psoriasis on the skin. I am however aware that some rheumatologists today chooses to take a calculated risk. If a flare-up occurs, they’ll discontinue the drug and treat the skin. Since Plaquenil is a "nice DMARD", that might be a good idea. I only know that I would not take the risk myself, with a history of severe skin psoriasis… Just thought you should be aware of the risk you are taking. > My rheumatologist and I are not impressed with the results of high doses > of nsaids in treating my PA.  As a result she wants to put me on disease > modifying medication.  Because of another disease and the meds i take > for it the only one she is comfortable using at this point is > chloriquin.  Has anyone taken this durg?  Success/side effects? > Thanks    Bruce

– Best regards / Med vennlig hilsen,       Aase Marit :) ))))))            ("Aw-Se-Mareet" from Norway) http://w1.2380.telia.com/~u238000263/flaker/docs/index.html

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My rheumatologist and I are not impressed with the results of high doses of nsaids in treating my PA.  As a result she wants to put me on disease modifying medication.  Because of another disease and the meds i take for it the only one she is comfortable using at this point is chloriquin.  Has anyone taken this durg?  Success/side effects? Thanks    Bruce

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RE: PA Is the med you mentioned the same as Plaquenil – the anti-malarial.  If it is it did not work for me – perhaps if you went to a major hospital you would find a doc who is more comfortable with all the new meds – I don’t know- I do know how frustrating it can be for you at this point – I have been there. I ended up going to NYC – an hour and twenty from my house each way- it is worth it however, since I have a doc who is supremo in rheumatology. I only need to go once a month if I am lucky.  Good luck, Michelle ps – consider joining our new mailing list for PA on onelist – I am moderating and so far we are small – only 14 members, Sending healing thoughts your way- and God Bless You, Michelle aka CTNATIVE Vaya Con Dios

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Bruce: If you’re referring to hydroxychloroquine (or Plaquenil), I’ve been taking that since January, ‘96.  It has worked for me as far as decreasing the intensity of the pain I was having.  I have had no side effects.  You do have to see an opthamologist every 6 months & have a visual field test every year, as there is a possible side effect of developing pigmentation on your retina.  I started on a dose of 200 mg twice a day for the first year, then my doc decreased it to 200 mg once a day.  I have had no problems with my eyes & the eye doc said at that dose there should be no problem, but they do need to keep tabs on things.  If you have any other questions, let me know. I’ll do my best to help. Good luck… Marie

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        Hi Bruce, I guess I’m surprised about the choice of chlorquine (or its derivation hydroxychloroquine) in PA.  There are other disease modifying agents with a much better track record for PA.  Sulfasalazine appears to be helpful in PA, particularly in patients with more symmetric polyarthritis.  Methotrexate is effective for both the arthritis of PA and the skin disease.  There are relatively small uncontrolled trials of other agents including cyclosporin, gold, azathioprine, calcitriol and etretinate as well as antimalarials.  Dr Chiu, who posts from New Zealand, has claimed success with minocycline but there are no published trials with this yet.         It sounds that your doc is right in wanting to add a DMARD to your NSAIDs.  I suggest you ask her what criteria she is using to recommend chloroquine. Hope this is helpful. Dr Susan  On > My rheumatologist and I are not impressed with the results of high doses > of nsaids in treating my PA.  As a result she wants to put me on disease > modifying medication.  Because of another disease and the meds i take > for it the only one she is comfortable using at this point is > chloriquin.  Has anyone taken this durg?  Success/side effects? > Thanks    Bruce

Susan Hoch                    

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Question:

I have noticed a number of posts relating to psoriatic arthritis. I have had skin psoriasis for over 20 years. I have had it a various times on the scalp, legs. elboes, knees, etc. Lately I have been experiencing pain in my left leg which is intermittent, and seems to radiate up and down my leg & also with pain in my shin bone. Could this be psoriatic arthritis? If so, what helps this condition.

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>I have noticed a number of posts relating to psoriatic arthritis. I have had >skin psoriasis for over 20 years. I have had it a various times on the scalp, >legs. elboes, knees, etc. Lately I have been experiencing pain in my left leg >which is intermittent, and seems to radiate up and down my leg & also with >pain >in my shin bone. Could this be psoriatic arthritis? If so, what helps this >condition.

Hi, Dwandless… in the beginning especially, it can be difficult to diagnose PA.  Have you seen a doctor about this pain yet?  I would not delay… if your regular doctor has no answers for you, or if he mentions "some kind of arthritis" without being very helpful about treatment, it would be time to ask for a referral to a rheumatologist (the specialist in all kinds of arthritis). Frankly, the description you gave doesn’t sound a lot like PA, but like I say, it can be different when it first starts.  However, it usually does hurt in a joint anyway, rather than radiating to the shin bone until there is advanced disease in the joint causing the radiating pain. Again, I am NOT a medical professional, so go and start getting some answers from the pro’s.  I would start with the regular doctor because you didn’t say specifically a joint pain, so it might be something else.   If you’d like to read more about PA, here’s a good site: http://www.aztec.co.za/users/drdoc/ One feature about PA (and RA for that matter) is that in the beginning, the pains are intermittant, and sort of jump around from joint to joint (making you think maybe I’m crazy and imagining this <G>).   Hope this helps! Best regards, LadyAndy2

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Question:

I realize that methotrexate questions have been popular in this newsgroup recently, so I hope you don’t mind if I post a few more… In regards to the injectable form of methotrexate, I was wondering if you had to go back to your doc to get the shot, or if you were offered the option of doing it yourself.   Also I was wondering how much of an improvement people experienced with their skin psoriasis when they take methotrexate for PA, and if people had noticed any improvement in their nails as well… Thanks a bunch in advance!!!!   Krista

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I take mtx orally, and have for about 3 years now.  I have always considered the PA to be the more important reason to take it, as it really affects my mobility and ability to function in the world, but as a nice side benefit, my P has almost completely cleared as well (for the first time in about 30 years…).  I actually have my hair combed back off my forehead now (would never dare to do that before), and have only the smallest of little spots of it here and there to remind me that if I ever stop the mtx, it will be back in no time.  And yes, the nails improved as well… I actually have a complete set of 10 that look normal at a time now (used to be at least 2 or 3 from each hand would be doing "their own thing"). (don’t know the percentage, but I used to have it all over… still have some scars left, but otherwise mostly clear.)

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  I realize that methotrexate questions have been popular in this   newsgroup   recently, so I hope you don’t mind if I post a few more…   In regards to the injectable form of methotrexate, I was wondering   if you   had to go back to your doc to get the shot, or if you were offered   the   option of doing it yourself.   Also I was wondering how much of an improvement people experienced   with   their skin psoriasis when they take methotrexate for PA, and if   people had   noticed any improvement in their nails as well…   Thanks a bunch in advance!!!!   Krista  Interesting questions.. By making the patient come for the injections – you can ensure that the appropriate monitoring gets done. There is no other reason to insist on it otherwise. Regarding the rash- i would expect the PA rash to improve in the majority. The nail changes may also improve – but thats a slow process. Regards drdoc http://www.aztec.co.za/users/drdoc/

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> In regards to the injectable form of methotrexate, I was wondering if you > had to go back to your doc to get the shot, or if you were offered the > option of doing it yourself.  

Hi Krista, I changed to injectable methotrexate about two months ago; I inject myself every Monday night.  The first time was terrible, now it isn’t so bad but I still don’t like it.  I’m still not sure I’m doing it right, have had a few bruises from this.  Oh yes, it seems I might be doing *slightly* better. Take Care — -Big Z

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>I realize that methotrexate questions have been popular in this newsgroup >recently, so I hope you don’t mind if I post a few more… >In regards to the injectable form of methotrexate, I was wondering if you >had to go back to your doc to get the shot, or if you were offered the >option of doing it yourself.   >Also I was wondering how much of an improvement people experienced with >their skin psoriasis when they take methotrexate for PA, and if people had >noticed any improvement in their nails as well… >Thanks a bunch in advance!!!!   >Krista

Krista, I have RA and take methotrexate by injection (see earlier posting).  I understand from various publications that I’ve read that metho. is VERY effective fighting the symptoms of PA.  Unfortunately, I don’t know anyone personally who has PA and been on metho.  Perhaps you should query your rheumatologist.  Good luck! CKK

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